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Gerardo Guillén Selected Research

Infections

1/2023Recombinant protein based on domain III and capsid regions of zika virus induces humoral and cellular immune response in immunocompetent BALB/c mice.
6/2017The tetravalent formulation of domain III-capsid proteins recalls memory B- and T-cell responses induced in monkeys by an experimental dengue virus infection.
1/2016Dengue encephalitis-associated immunopathology in the mouse model: Implications for vaccine developers and antigens inducer of cellular immune response.
8/2015A novel tetravalent formulation combining the four aggregated domain III-capsid proteins from dengue viruses induces a functional immune response in mice and monkeys.
7/2014Generation and characterization of potential dengue vaccine candidates based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus.
7/2014Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines.
12/2013Olive baboons: a non-human primate model for testing dengue virus type 2 replication.
6/2012Recombinant nucleocapsid-like particles from dengue-2 induce functional serotype-specific cell-mediated immunity in mice.
3/2011The chimeric protein domain III-capsid of dengue virus serotype 2 (DEN-2) successfully boosts neutralizing antibodies generated in monkeys upon infection with DEN-2.
12/2009Viremia and the magnitude of the immune response upon infection of green monkeys with dengue virus type 2 are strain-dependent.
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Gerardo Guillén Research Topics

Disease

28Dengue (Dengue Fever)
01/2016 - 08/2003
11Infections
01/2023 - 01/2008
5Viremia
01/2019 - 08/2003
3COVID-19
01/2022 - 02/2021
3Neoplasms (Cancer)
02/2021 - 12/2005
3Virus Diseases (Viral Diseases)
06/2017 - 02/2010
2Prostatic Neoplasms (Prostate Cancer)
01/2019 - 01/2008
2Viral Encephalitis
01/2016 - 04/2009
2Encephalitis (Encephalitis, Rasmussen)
01/2016 - 01/2013
2Necrosis
06/2012 - 02/2007
1Vesicular Stomatitis
06/2023
1Pneumonia (Pneumonitis)
02/2021
1Severe Dengue
01/2019
1Hepatitis B
01/2018
1Reinfection
06/2017
1Meningococcal Infections
02/2010
1Breast Neoplasms (Breast Cancer)
01/2008
1Myocardial Infarction
02/2007
1Body Weight (Weight, Body)
02/2007
1Coronary Occlusion
02/2007
1Ulcer
09/2006
1Diabetic Foot
09/2006
1Wounds and Injuries (Trauma)
09/2006
1Uterine Cervical Neoplasms (Cancer of the Cervix)
12/2005

Drug/Important Bio-Agent (IBA)

24VaccinesIBA
01/2022 - 08/2003
21Proteins (Proteins, Gene)FDA Link
12/2021 - 08/2003
9Neutralizing AntibodiesIBA
01/2019 - 08/2003
9Capsid Proteins (Capsid Protein)IBA
06/2017 - 01/2007
7AntibodiesIBA
06/2023 - 08/2003
7Recombinant ProteinsIBA
07/2014 - 01/2008
5Antiviral Agents (Antivirals)IBA
06/2017 - 01/2007
5Recombinant Fusion ProteinsIBA
07/2012 - 04/2006
4Dengue VaccinesIBA
07/2014 - 04/2009
3AntigensIBA
01/2023 - 01/2013
3Carrier Proteins (Binding Protein)IBA
06/2011 - 02/2009
2Peptides (Polypeptides)IBA
02/2021 - 12/2005
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2019 - 01/2008
2Interferon-gamma (Interferon, gamma)IBA
07/2014 - 06/2012
2Combined VaccinesIBA
07/2014 - 06/2012
2Viral AntigensIBA
07/2012 - 12/2008
2EpitopesIBA
07/2012 - 12/2008
2Immunoglobulin M (IgM)IBA
01/2008 - 08/2003
2Amino AcidsFDA Link
10/2006 - 01/2004
1Subunit VaccinesIBA
12/2021
1Protein Kinases (Protein Kinase)IBA
02/2021
1Testosterone (Sustanon)FDA Link
01/2019
1aluminum sulfate (alum)IBA
01/2015
1OligodeoxyribonucleotidesIBA
01/2015
1Interferon Type IIBA
07/2014
1Immunoglobulin G (IgG)IBA
07/2012
1CytokinesIBA
06/2012
1Polysaccharides (Glycans)IBA
05/2012
1Indicators and Reagents (Reagents)IBA
12/2009
1Hormones (Hormone)IBA
01/2008
1AndrogensIBA
01/2008
1Oxidants (Oxidizing Agents)IBA
02/2007
1Saline SolutionIBA
02/2007
1gamma- aminobutyryl- 2- methyltryptophyl- 2- methyltryptophyl- 2- methyltryptophyl- lysinamideIBA
02/2007
1Epidermal Growth Factor (EGF)IBA
09/2006
1Glycoproteins (Glycoprotein)IBA
08/2003

Therapy/Procedure

1Therapeutics
01/2019
1Surgical Amputation (Amputations)
09/2006
1Immunotherapy
12/2005